James Church

Wellcome Trust Clinical Research Training Fellow

My primary research interests are in gut structure and function and how they might impact on the health and immune function of children in low-income countries. I am currently based in Harare, Zimbabwe as part of my PhD fellowship where I intend to gain a more in-depth understanding of why oral vaccines are less effective when given to children in developing countries. I am exploring associations between intestinal factors (such as enteropathogen carriage) and oral vaccine immunogenicity. I will also be capitalising on the SHINE trial in Zimbabwe to explore the impact of a water, sanitation & hygiene intervention on oral vaccine immunogenicity.