SHINE Trial

shineIn Zimbabwe, we are undertaking a cluster-randomized trial of improved infant feeding and/or improved water, sanitation and hygiene (WASH) among 5200 infants in two rural districts, to reduce EED and improve growth and anaemia in early life. We are characterising in detail the biomedical pathway linking WASH and impaired growth and development in infancy.  In linked substudies we are evaluating the role of the microbiota in malnutrition; the impact of maternal infection and inflammation on adverse birth outcomes; the role of mycotoxins in enteropathy and stunting; and the impact of these interventions in HIV-exposed infants.

You can read more about the SHINE Trial here

https://clinicaltrials.gov/ct2/show/NCT01824940.